Let's consider a couple of examples of how you would go from subject to defining topic to finding a research question and finally making a thesis. Suppose you were taking a course on art history and you were learning in the course about modern 20th-century painters - Matice and Chagall, Picasso and many others. You might be asked to write a term paper about Picasso, or you might choose Picasso because he's a painter you were particularly interested in. So, the general subject area for your research paper might be, Picasso.